Is Factor V Leiden a Risk Factor for Fetal Loss?

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Recurrent Pregnancy Loss in a Subject with Heterozygote Factor V Leiden Mutation; a Case Report

Recurrent pregnancy loss is usually defined as the loss of two or more consecutive pregnancies before 20 weeks of gestation, which occurs in approximately 5% of reproductive-aged women. It has been suggested that women with thrombophilia have an increased risk of pregnancy loss and other adverse pregnancy outcomes. Thrombophilia is an important predisposition to blood clot formation and is cons...

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Is factor V Leiden a risk factor for thrombotic microangiopathies without severe ADAMTS 13 deficiency?

About 60% of patients diagnosed with acute thrombotic thrombocytopenic purpura (TTP) display a severe ADAMTS13 deficiency. Recently, Raife et al. concluded from a small case series, that factor V Leiden (FVL) might constitute a risk factor for acute thrombotic microangiopathy (TMA) without severe ADAMTS13 deficiency. Therefore, we determined ADAMTS13 activity and FVL carrier-ship in 256 consecu...

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Factor V Leiden is not a risk factor for myocardial infarction among young women.

Several large-scale studies indicate that factor V Leiden (FVL) is not associated with an increased risk of acute myocardial infarction (MI) in middle-aged or elderly populations.1-7 However, Rosendaal et al8 have hypothesized that FVL might increase the risk of myocardial infarction among women less than 45 years of age, particularly in the subgroup of smokers. Specifically, in a study of 84 w...

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Factor V Leiden Is Not a Risk Factor for Myocardial Infarction Among Young Women

Several large-scale studies indicate that factor V Leiden (FVL) is not associated with an increased risk of acute myocardial infarction (MI) in middle-aged or elderly populations.1-7 However, Rosendaal et al8 have hypothesized that FVL might increase the risk of myocardial infarction among women less than 45 years of age, particularly in the subgroup of smokers. Specifically, in a study of 84 w...

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Factor V Leiden Mutation Is a Risk Factor for Cerebral Venous Thrombosis

Background and Purpose—Different coagulation disorders have been associated with cerebral venous thrombosis (CVT). Until now, fewer than 50 patients have been reported with CVT and the factor V Leiden (FVL) mutation. Although the prevalence of FVL-positive patients with CVT ranged from 10% to 25%, it was as low as 0.5% to 3% in the control groups. Most other studies had not systematically searc...

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ژورنال

عنوان ژورنال: Acta Medica (Hradec Kralove, Czech Republic)

سال: 1999

ISSN: 1211-4286,1805-9694

DOI: 10.14712/18059694.2019.150